A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...

If I asked you, dear reader, to come up with a shortlist of the most monumental scientific achievements of the last century, chances are the Human Genome Project (HGP) would appear somewhere on that ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA – its genome – and segregate it equally ...

Some scientists that speak of poking and prodding DNA mean it literally—that is, they are talking about physically nudging chromatin to assess DNA’s physical nature. And they would add, just as ...

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren’t ...

A team of scientists studying cell division developed a special light microscopy system and used it to analyze the molecular density of cellular environments. Their results provide a novel insight ...

A French research team led by CNRS scientists has discovered that cells are able to retain a memory of a previous perturbation within the 3D structure of their genome, independently of their DNA ...

Mechanistic model for G9a-H3K9me2 in preserving centromere integrity. G9a-mediated H3K9me2 at centromeres prevents the invasion of H3K9me3 into core centromeric domains, which ensures proper ...