Genetic testing is transforming depression treatment by tailoring antidepressants to your DNA for better results and fewer ...

The gene encodes an enzyme in the liver called CYP2D6. Subsequently, they tested different drug compounds on engineered cell models to determine how the effect of the compound was influenced by ...

Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates) interacts with QUERCETIN Some medications are changed and broken down by the liver. Quercetin might change how quickly ...

Concomitant use or discontinuation of CYP2D6 inhibitors ... Risk of serotonin syndrome with serotonergic drugs (eg, SSRIs, SNRIs, TCAs, triptans, 5-HT3 antagonists, mirtazapine, trazodone ...

Cardiovascular disease. Angle-closure glaucoma. Seizures. Psychosis. Poor metabolizers (those with reduced CYP2D6 activity). Avoid abrupt cessation. Write ℞ for smallest practical amount.

Authors: Siphokazi Tshoko, Yonela Mgwili, Siphamandla Nqunqa, Takalani Mulaudzi, Noluthando Mayedwa, Emmanuel Iwuoha Email ...

Key genetic markers include: CYP2D6 and CYP2C19: These liver enzymes metabolize many antidepressant medications. Variations can classify individuals as poor, intermediate, normal, or ultrarapid ...