This is achieved by infecting a pool of Cas9- expressing cells with ... sequencing datasets that emerge from each single-cell CRISPR screen. “These days, we routinely create close to 10 billion ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.