Recent research from Duke University has demonstrated a promising new approach that could be used to treat a rare and complex ...

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.

called “spacers” into the CRISPR locus in the genome of the bacterial host. These spacers are later transcribed into crRNA that are loaded on Cas nucleases to target them to cleave and block recurring ...

CRISPR-Cas9 editing leads to widespread loss of the targeted ... To investigate how Cas9 gene editing affected T cells, the researchers targeted the first exon of the TRAC locus, which encodes the T ...

And North Carolina State University's Rodolphe Barrangou, Ph.D., uses a different CRISPR enzyme to edit genes. This technique underpins the work of Locus Biosciences. With this foundation ...

A single genetic switch could potentially treat a rare but severe childhood disorder. Prader-Willi Syndrome (PWS) affects approximately 1 in 15,000 newborns, causing insatiable hunger, obesity ...

In the world of biopharmaceutical innovation, 2024 will be remembered as CRISPR’s breakout year. In the spring, five patients with sickle cell disease began treatment with Casgevy, the first FDA ...

GenScript now provides high-quality, sequence-verified HDR templates to help users edit their CRISPR experiments more ... GFP KI at RAB11A Locus in HEK293 cells using electroporation with 5 ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...