An investigational therapeutic vaccine showed clinical effectiveness in patients with human papillomavirus (HPV)16-positive cervical intraepithelial neoplasia grade 3 (CIN3), according to results ...
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A therapeutic HPV vaccine could eliminate precancerous cervical lesions, clinical trial suggests"Nearly all premalignant cervical lesions and cervical cancers ... In those with grade 3 cervical intraepithelial neoplasia (CIN3), cells are already on the path toward malignancy.
[36] Detection of E6/E7 mRNA was strongly correlated with severity of the lesion; more than 90% of CIN 3 cases and all five carcinomas revealed E6/E7 mRNA. Agnes Kathrine Lie, MD, PhD, Department ...
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