Buffalo’s run defense was equally stout, holding Carolina to 77 yards on 28 rushes (an average of 2.75 yards per carry). The Bills sacked Cam Newton six times, with Jerry Hughes recording two sacks and Lorenzo Alexander, Shaq Lawson, Jordan Poyer, and Eddie Yarbrough each adding a sack of Newton.

Buffalo also has four players listed as questionable in Terrel Bernard, Matt Milano, Dalton Kincaid and Maxwell Hairston, who has a chance to make his NFL debut after missing the first six games with a knee injury.

Riding a two-game losing streak the Bills take on the Panthers in a game they need to win. Here's Sal Maiorana's preview.

Defensive tackle Larry Ogunjobi and defensive end Michael Hoecht are back from six-game suspensions to start the season for violating the NFL’s policy performance-enhancing drugs (PED) policy. Both were added to the 53-man roster on Tuesday and have yet to debut for Buffalo after signing as free agents this offseason.

The Buffalo Bills have lost two in a row and are now in dire need of a victory as they head to Charlotte to take on the Carolina Panthers on Sunday at 1 p.m. It

Game 1 of the "Fall Classic" went down in Toronto on Friday. The Blue Jays took a huge 11-4 win over the Los Angeles Dodgers thanks to a nine-run effort in the sixth inning. Making an appearance up the QEW was the Buffalo Bills ... or at least Dion Dawkins.

The wives and girlfriends of Buffalo Bills players traded their game-day outfits for jerseys and cleats on Tuesday at Highmark Stadium for the annual charity flag football game to tackle hunger.

Buffalo Bills' GM Brandon Beane enjoyed a very busy offseason. However, ESPN's senior NFL writer Bill Barnwell ranked all 32 offseasons into tiers, with Buffalo's falling into the 'slightly below expectations' bucket.