Hemoglobin is essential for carrying oxygen throughout the body via red blood cells. Individuals with ... There are two main ...

the cells can also be induced to differentiate and produce a final reticulocyte (immature red blood cell) product. Beta-thalassemia is a blood disorder resulting in the reduction of haemoglobin ...

A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce ...

Molecules of sickle-cell hemoglobin stick to one another, forming rigid rods. These rods cause a person's red blood cells ... in a frameshift One form of beta-thalassemia Deletion One or more ...

Ono Pharmaceuticals has secured the global rights to sapablursen, an RNA-targeting therapy by Ionis to treat polycythemia ...

Her parents encouraged her to partake in a trial for a CRISPR -based therapy for sickle-cell disease and beta-thalassemia, another debilitating genetic blood disorder. The therapy, Casgevy, was made ...

Japan's Ono Pharmaceutical is handing over $280 million upfront to acquire Ionis Pharmaceuticals’ phase 2-stage antisense ...

Similarly, some gene therapies, especially for blood disorders such as beta-thalassemia, require the harvesting of patients' blood stem cells, insertion of a therapeutic gene, and expansion of the ...

From STAT’s Andrew Joseph: AstraZeneca said this morning it was buying the Belgian cell therapy company EsoBiotec for $425 million upfront, building out another cancer-targeting approach.