The Scientist3y
Many Bacteria and Archaea Promoters Work Forward and Backward
While previous research had described bidirectional promoters in eukaryotes, as well as in a few bacteria and archaea species, the new study establishes divergent transcription—the reading of genes in ...
Extreme mutation hotspot in bacteria discovered, with high mutation rates linked to transcriptional activation
A new study published in PLOS Genetics has identified an extreme mutational hotspot within the genome of Pseudomonas ...
Nature2y
RNA Transcription by RNA Polymerase: Prokaryotes vs Eukaryotes
A striking example of the specialization of sigma factors for different gene promoters is provided by bacterial sporulation in the species Bacillus subtilis. This bacterium exists in two states ...
Informationsdienst Wissenschaft6d
Extreme Mutation Hotspot in Bacteria Discovered: Study Links High Mutation Rates to Transcriptional Activation
Max Planck researchers discovered a 5,000-fold increase in the mutation rate in the genome of *Pseudomonas fluorescens*. The mutation regularly occurred in the promoter region of the *rpoS* gene and ...