Triple-negative breast cancer (TNBC) refers to any breast cancer that does not express the oestrogen receptor (ER), progesterone receptor (PR) and HER2 receptor; this disease subtype accounts for ...

The new drug target is the BCL11A gene, which researchers zeroed in on by studying 3,000 breast cancers and the genes that affect stem cells and developing tissue. Dr. Pentao Liu ...

Scientists pinpoint druggable target in aggressive breast cancer. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2022 / 10 / 221025153406.htm.

BCL11A: Evidence for neuroprotective effect Date: September 14, 2021 Source: University of Bonn Summary: The neurotransmitter dopamine influences the activity of a wide variety of brain areas.

In 2021, research led by Ryan Flynn, MD, Ph.D., and his mentor, Nobel laureate Carolyn Bertozzi, Ph.D., opened a new chapter in biology, characterizing a new kind of player on the cell surface ...

Identifying new ways to target proteins involved in human diseases is a priority for many researchers around the ... New mapping method illuminates druggable sites on proteins (2024 ...

The researchers suspect that BCL11A plays a protective role for neurons. The study is now published in Cell Reports. ... For example, the target region was not the entire striatum, ...