But each round of this process is a roll of the ... a safeguard—some way for high-affinity B cells to pause mutating and hold onto their best traits. The question was how that safeguard worked. In ...

guiding B-cell progenitors through the maturation process. According to the research, this is an exceptionally subtle process ...

Appre-ciating the immunological relay race may provide clues to enhancing the collaboration between DCs, B and T cells in vaccine development and provide approaches for strategically fumbling the ...

They also show that models learned from nonsynonymous mutations and from out-of-frame sequences are different, prompting new questions about germinal center function. Strengths of the study include an ...