Despite advancements in melanoma therapy, the prognosis remains unfavorable for many patients. The proteasome inhibitor MG132 has shown therapeutic potential through pathway regulation, yet its ...

In multicellular organisms, the total number of cells is a balance ... is induced through apoptosis. A disruption of this delicate balance can lead to the development of cancer.

In general, though not always, this is an early event in apoptosis and is thought to be a signal to neighbouring cells that a cell is ready to be phagocytosed. Annexin-V is a specific PS-binding ...

Researchers at Karolinska Institutet have uncovered a unique ability of a special subtype of natural killer cells in the ...

low glucose slows down the consumption and exhaustion of uridine nucleotides needed to fuel cancer cell growth and hinders resulting apoptosis, or death, in cancer cells,” said Possemato. These ...

For the in vitro component, cancer cell lines were exposed to electrical ... pulses correlated with increased levels of apoptosis, as measured by Annexin-V staining. The data suggest that the ...

These dyes can be multiplexed with Incucyte ® Annexin V, Caspase-3/7 or Cytotox reagents for simultaneous readouts of apoptosis or cytotoxicity. Simple to use – harvest cells, add dye ...