Lundbeck has gained orphan drug designation (ODD) from Japan’s Ministry of Health, Labor and Welfare (MHLW) for amlenetug to ...

The full-length IgG format also enables further modification of the Fc region for enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) or to prevent binding to Fc-γ receptors on immune ...

Source: Sino Biological Inc. To mediate antibody-dependent cellular cytotoxicity ... proteolytic cleavage or increase affinity for IgG Fc region have shown promising results.

Proteintech has designed recombinant antibodies featuring the company's FcZero backbone, engineered to silence the Fc domain ...