A team of researchers has developed a method that could transform the field of protein engineering. The new approach, called ...

Chinese scientists have developed a novel AI-guided protein engineering strategy that enables faster, cost-effective, and highly accurate protein design. A group of scientists in China, led by Profess ...

Fourteen million people worldwide suffer from enlarged hearts, or hypertrophic cardiomyopathy (HCM), a genetic disease that ...

The scientists noted that adenine base editors may overcome many of the challenges associated with other gene therapy approaches because the treatment is better tolerated by cells compared to Cas9 ...

In vivo base editing enables precise, single-nucleotide changes to DNA without double-strand breaks. A recent application in ...

New research demonstrates the potential of precise genome editing technologies, called adenine base editors, to correct disease-causing mutations in stem cells from patients with X-linked chronic ...

Metagenomi Adenine Base Editors (ABEs) demonstrated over 95% genome targetability Simultaneous ABE triplex editing resulted in over 95% protein knockdown in primary T-cells ABE demonstrated highly ...

Genomic alteration using adenine base editors demonstrated the most potency in restarting fetal hemoglobin expression in cells of patients with sickle cell disease, study results showed. The ...

Fusion of a rice endogenous N-methylpurine DNA glycosylase to a plant adenine base transition editor ABE8e enables A-to-K base editing in rice plants Beijing Zhongke Journal Publising Co. Ltd. Journal ...