When Kerry Washington announced Demi Moore as the Golden Globes winner for Best Comedy/Musical Actress on Sunday night, the crowd reacted in surprise jubilation — and that was before The Substance star brought the house down with the best acceptance speech of the night.

In an evening of surprises at the Golden Globes, perhaps the most satisfying win of the night came when Demi Moore took home the Best Actress in a Comedy/Musical award for The Substance. It was a rarity in Hollywood awards season: a body horror satire with a 62-year-old female lead that spits in the face of the entertainment industry’s sexism and splatters enough blood and guts at the screen to make even David Cronenberg nauseous.

Demi Moore has made a triumphant return to the Golden Globes, winning best actress for a role in a body horror which has revitalised her career. The 62-year-old gave an impassioned speech as she collected her award, telling the audience she was "at a low point" in her career before being cast in The Substance.