The role of syncytia during viral infections - PubMed
WEBSep 21, 2021 · RSV is characterized by syncytia, which are multinuclear cells created by cells that have fused together. We use a mathematical model to study how different assumptions about the viral production and lifespan of syncytia change the resulting infection time course.
The role of syncytia during viral infections - ScienceDirect
WEBSep 21, 2021 · RSV is characterized by syncytia, which are multinuclear cells created by cells that have fused together. We use a mathematical model to study how different assumptions about the viral production and lifespan of syncytia change the resulting infection time course.
The role of syncytia during viral infections - ScienceDirect
WEBSep 21, 2021 · RSV is characterized by syncytia, which are multinuclear cells created by cells that have fused together. We use a mathematical model to study how different assumptions about the viral production and lifespan of syncytia change the resulting infection time course.
Respiratory syncytial virus entry and how to block it
WEBFeb 5, 2019 · Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract disease in young children and elderly people. Although the virus was isolated in 1955, an...
Respiratory syncytial virus infection in adults - UpToDate
WEBAug 22, 2024 · The clinical manifestations, diagnosis, treatment, and prevention of RSV in adults will be reviewed here. Topic reviews that discuss the virology and pathogenesis of RSV, as well as RSV infection in children, are presented separately.
Respiratory Syncytial Virus - SARS, MERS and other Viral Lung ...
WEBJun 1, 2016 · It was re-termed respiratory syncytial virus, as it causes cells to fuse with neighboring cells, creating large multinucleated syncytia. RSV has been classified into two distinct subgroups (A and B), based on antigenic variability .
A new mechanism of respiratory syncytial virus entry inhibition …
WEBRespiratory syncytial virus (RSV) infection is a major cause of lower respiratory tract disease (LRTD) in young children and elderly individuals. In 2019, RSV was estimated to be responsible for more than 33 million episodes of acute LRTDs, ... resulting in the formation of multinucleated syncytia.
Direct cell-to-cell transmission of respiratory viruses: The ... - PLOS
WEBJun 28, 2018 · B) The formation of syncytia involves the fusion of infected cells with adjacent target cells and remains an important mechanism of direct cell-to-cell spread of viral components. This mechanism of spread has been reported for influenza, HMPV, PIVs, RSV, and MeV, among others.
Respiratory Syncytial Virus - PMC - National Center for …
WEBClinically known for about a century but not isolated until 1956, respiratory syncytial virus (RSV) represents the most common cause of bronchiolitis, outranking all other microbial pathogens as a cause of pneumonia or bronchiolitis in infants under the age of one.
Virus-Induced Cell Fusion and Syncytia Formation
WEBNov 24, 2023 · Multinucleated syncytia are associated with the lung tissue damage in SARS-CoV and MERS-CoV infections. Autopsy reports from MERS-CoV-infected patients and SARS patients revealed the presence of infected giant multinucleated syncytia cells in the lungs, which are mostly of epithelial origin (Alsaad et al. 2018 ; Franks et al. 2003 ; …